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Year : 2021  |  Volume : 4  |  Issue : 1  |  Page : 22-25

Catheter-related blood stream infections among children on hemodialysis over 7 years: A single-center experience

Department of Paediatric Nephrology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates

Correspondence Address:
Gurinder Kumar
Department of Paediatrics, Sheikh Khalifa Medical City, Al Karamah Street, Abu Dhabi
United Arab Emirates
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajpn.ajpn_31_20

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Patients with end-stage kidney disease frequently require hemodialysis (HD) through central venous catheters (CVCs) as a bridge to renal transplantation. However, longevity of CVCs is affected by the occurrence of CVC-related bloodstream infections (CVC-RBI). This retrospective study evaluated the outcomes of CVCs inserted for HD, with specific attention to rates and etiology of CVC-RBI. Over 7 years between January 2010 and December 2016, 39 patients, aged 2–15 years, were admitted for HD for ESRD in the Department of Pediatric Nephrology, Sheikh Khalifa Medical City, Abu Dhabi, UAE. The most etiology for ESRD was renal dysplasia (28.2%). Tunneled cuffed CVC was inserted most commonly in the right internal jugular vein (40.2%). The most common reason for change of CVC was CVC-RBI (28.9%). The estimated rate of CVC-RBIs was 1.72/000 CVC days. Staphylococcus aureus was the most common (28.6%) etiology. CVC longevity was significantly influenced by the occurrence of CVC-RBI (P < 0.001), and the rates of CVC-RBI were significantly different between patients with less or more than 200 CVC days (P = 0.002). Most patients either continued on HD (48.7%) or underwent kidney transplantation (28.2%). This study highlights that rates of CVC-RBI were low but were associated with prolonged CVC use.

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